A review of studies on the comorbility between depression and cardiovascular risk factor in old age.
We consider the magnitude of diagnosis of depression in old age often sub-diagnosed with the relevant risks, including the high cardiovascular morbidity and mortality in order to make appropriate treatment of both pathologies. We evaluated risk factors, genetic, personality, similar symptoms of geriatric depression with medical illness, comorbidity, pathophysiologic mechanisms, neuroendocrine, platelet activation, hypercoagulability, inflammatory cytokines, and endothelial dysfunction.
Psychopharmacological controlled studies are presented to perform an adequate antidepressant choice considering the frequent polypharmacy and possible interactions in this age group. Likewise the statement of the European Psychiatric Association (EPA), with support from The European Association For The Study Of Diabetes (EASD) and the European Society of Cardiology (ESC) for interdisciplinary care of psychiatric patient
Key Words Depression in old age, sub diagnosis, cardiovascular events, antidepressants.